Apr 3, 2024 · Spindle cell lipoma and pleomorphic lipoma are benign adipocytic tumors, currently regarded as morphologic variants of a single neoplasm.

Pleomorphic lipoma is a relatively uncommon benign adipocytic tumor that shows a variable lipomatous component, spindle-shaped cell component, and floret-like giant cells with nuclear pleomorphism, and was first described by Shmookler and Enzinger in 1981.

Spindle cell lipoma (SCL) is a benign adipocytic tumor that primarily occurs in the subcutis of the posterior neck, upper back, and shoulder, particularly of middle-aged males. SCL and pleomorphic lipoma (PL) represent a morphological spectrum of one disease process.

Pleomorphic lipomas, like spindle-cell lipomas, occur for the most part on the backs and necks of elderly men, and are characterized by floret giant cells with overlapping nuclei. [1]: 625. Most cases of pleomorphic lipoma are seen in the subcutaneous tissue of the back, shoulder, and posterior neck. [2] .

Oct 13, 2020 · A lipoma is a lump of fatty tissue that grows just under the skin. Lipomas move easily when you touch them and feel rubbery, not hard. Most lipomas aren’t painful and don't cause health problems so they rarely need treatment. If a lipoma is …

Oct 6, 2022 · A pleomorphic lipoma is a non-cancerous tumour made up of fat and spindle cells. This tumour commonly starts around the upper back and neck but can be found almost anywhere in the body. Most grow just under our skin where they feel like a soft lump. Another name for this tumour is spindle cell lipoma. This picture shows the typical microscopic ...

Pleomorphic lipomas are benign tumours, which display atypical cytologic features that may be confused with liposarcoma. Histology of pleomorphic lipoma. Sections of pleomorphic lipoma show a circumscribed fatty tumour with mature fat admixed with more cellular areas (figure 1).

Sep 19, 2022 · Atypical spindle cell/pleomorphic lipomatous tumors or atypical spindle cell lipoma are benign adipocytic soft tissue neoplasms with a variable proportion of atypical spindle cells, pleomorphic cells adipocytes and other cells with no risk for …

Background: Spindle cell lipomas (SL) and pleomorphic lipomas (PL) are rare variants of lipomas, occurring predominantly in the head and neck region. Laryngeal SL/PL is very uncommon and causes obstructive symptoms needing immediate intervention.

Jun 1, 2022 · This review will focus on the quintessential RB1-deficient mesenchymal neoplasm, spindle cell/pleomorphic lipoma, and the emerging families of related tumors currently grouped under the rubric of atypical spindle cell/pleomorphic lipomatous tumor.