Jul 16, 2025 · The knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information.

Jul 17, 2025 · The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins …

Jul 17, 2025 · WT1 is a tumor suppressor gene associated with the development of Wilms' Tumor, from which it was named. Mutations in exon 7 and 9 of WT1 have been recurrently identified in …

Jul 17, 2025 · This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a …

Jul 17, 2025 · The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell …

Jul 17, 2025 · Various mutations have been described for this gene and have been linked to human diseases related to impaired immune function such as severe combined …

Jul 17, 2025 · The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix …

Jul 17, 2025 · This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two …

Jul 17, 2025 · The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family …

Jul 17, 2025 · Complete information for ALK gene (Protein Coding), ALK Receptor Tyrosine Kinase, including: function, proteins, disorders, pathways, orthologs, and expression.