Background Benign multiple sclerosis (MS), characterised by minimal disability despite long disease duration, remains poorly understood in terms of its determinants and prognostic implications. While ...

Objectives To assess the diagnosis of somatic symptom disorder (SSD) in patients with unexplained neurological symptoms occurring after SARS-CoV-2 infection, also referred to as long COVID. Design ...

Frontal lobe brain sagging syndrome is recently described syndrome, though its natural history and pro- gression remains unknown. We present a 68-year-old female with progressive worsening of ...

Background Pain is an important symptom in Huntington’s disease (HD), however, not systematically studied and understood. The objective of the current study is to assess the prevalence of pain, pain ...

Biography Dr Lucy Vanes is a lecturer in Neuroscience and Psychology at the Department of Neuroimaging, King’s College London. She completed her PhD in 2017, studying the neural correlates of ...

Background Amyloid-related imaging abnormalities due to oedema (ARIA-E) or haemosiderin deposits (ARIA-H) have been associated with the use of monoclonal antibodies, such as lecanemab, for the ...

Background Evidence of best practice for long term physical activity Huntington’s disease (HD) is lacking, due in part, to inherent challenges in the delivery and evaluation of such life-style ...

Benign positional vertigo (BPV) is the most frequent cause of vertigo seen in office practice, with a lifetime incidence of at least 8%.1 While most patients give a diagnostic history—brief spinning ...

Uncomplicated Strümpell's disease (Strümpell's familial spastic paraplegia) with a dominant mode of inheritance is recorded in six families. The neuropathological findings in two cases from these ...

Seven patients with subdural empyema were initially treated by antibiotics without surgery. Six have recovered without sequelae. One required delayed surgery and has recovered with epilepsy. The ...

Enroll-HD is a global research platform. Key elements of the platform’s infrastructure include global study management and governance, standardised informed consent forms (ICFs) and site contracts, ...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by the loss of both upper and lower motor neurons. Approximately 10% of patients with ALS have a family history of the ...