The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are ...

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale ...

The San Francisco 49ers dominated their Week 11 matchup as the Arizona Cardinals were exposed once again.

For the first time since Week 1, the San Francisco 49ers had all of their starters back. Sure enough, it equates to their ...

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

Watch the San Francisco 49ers' top plays from the team's 41-22 win against the Arizona Cardinals in Week 11. Watch the best ...

Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and ...

What's the Arizona Cardinals vs San Francisco 49ers score? Follow our live score updates for latest news, highlights, ...

The Arizona Cardinals‘ attempt to rebound from a divisional blowout was unsuccessful on Sunday, as they were dominated by the ...

» Not only did the Niners’ tight end catch a touchdown of his own, but he was instrumental on the 49ers’ third touchdown of ...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host ...

Kyle Madson of Niners Wire takes Cardinals fans behind enemy lines before the Week 11 Cardinals vs. 49ers showdown.