To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

This RCE method utilizes bio-orthogonally assigned pseudouridine-modified codons (ΨCodons: ΨGA, ΨAA, or ΨAG) at designated mRNA transcripts for ncAA incorporation in mammalian cells.

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

The genomes of species from bacteria to Drosophila show unique biases for particular synonymous codons—varying triplet base pairs that code for the same amino acids—but it has been unclear if such ...

The advent of mRNA vaccine technology has led to safe and strong protection against Covid-19. But proponents say this is just the beginning. Dr. Drew Weissman and Katalin Karikó of the University ...

We asked experts about how the technology works, its safety and its potential in medicine. By Nina Agrawal Health Secretary Robert F. Kennedy Jr. has repeatedly questioned the safety of mRNA ...