Is it safe to take acetaminophen? Yes, it's usually safe when taken according to the directions on the label. But taking more than that can cause liver damage, liver failure, or even death.

This separates the liver into three zones with different tasks ... we wanted to test how well this drug worked to repair the ...

Acetaminophen (APAP), although recognized as a safe and effective antipyretic and analgesic drug, can lead to acute liver failure if taken in excess.