The San Francisco 49ers lost a few of their key pieces in Week 7, including Deebo Samuel, who only played four snaps.

When the Dallas Cowboys travel to face the San Francisco 49ers in Week 8, the 49ers may be without another one of their key offensive weapons.

The San Francisco 49ers, eventually, showed how much they value Brandon Aiyuk shortly before the start of the season by ...

Afterwards, head coach Kyle Shanahan added more detail around his illness, making it easy to understand why Samuel wasn't ...

Brock Purdy’s three interceptions for the 49ers with no touchdown passes led to a career-low 36.7 passer rating.

The San Francisco 49ers just lost yet again to the Kansas City Chiefs, this time by a score of 28-18. Here are the 49ers' grades for this embarra ...

The 49ers’ already depleted offense took a hit on Sunday as Brandon Aiyuk and Deebo Samuel were deemed out for the second ...

Samuel was limited on Sunday in the 28-18 loss to the Chiefs with an illness. He played sparingly but recorded no stats. So ...

The biggest concern from Sunday's loss to the Kansas City Chiefs—besides the San Francisco 49ers' falling to 3-4 on the ...

The 49ers kept the score close until early in the fourth quarter on Sunday, but it was a rough day all-around in the 28-18 ...

San Francisco 49ers head coach Kyle Shanahan discusses Sunday’s 28-18 loss to the Kansas City Chiefs, believes that Brandon ...

San Francisco 49ers star wideout Deebo Samuel left his team's home game against the Kansas City Chiefs on Sunday with an illness and was later ruled out.