Brock Purdy threw three touchdown passes in his return from a toe injury, Christian McCaffrey had two rushing touchdowns and ...

A healthy 49ers offense turned to its stars in San Francisco's 41-22 victory over the Arizona Cardinals on Sunday at State ...

The Arizona Cardinals set a franchise record with 17 penalties during their latest loss, a 41-22 disaster vs. the 49ers, and it could prove costly ...

Setting NFL records is cool - but winning is much cooler in the eyes of Arizona Cardinals QB Jacoby Brissett. In the process ...

Arizona had 488 yards of offense, eclipsing San Francisco by more than 200. Jacoby Brissett set an NFL record for completions, had a career high passing and threw two touchdown passes. The Cardinals ...

Detroit Lions middle linebacker Alex Anzalone takes down Philadelphia Eagles running back Saquon Barkley for a loss of 10 ...

The Cardinals have now lost seven of their last eight, including two straight blowouts to divisional opponents.

Brock Purdy returned, and more importantly, returned to form in a 41-22 blowout victory over Arizona. Purdy was 19-26 for 200 ...

The San Francisco 49ers put on a show on the road against the Arizona Cardinals, scoring 41 points on 12 drives, generating ...

Walter Nolen III, a defensive tackle out of Ole Miss, was scouted by the 49ers, who instead took Mykel Williams with the No.

Walter Nolen III, a defensive tackle out of Ole Miss, was scouted by the 49ers, who instead took Mykel Williams with the No.

A season-long 34-yard carry highlighted a productive and explosive day for Rams running back Kyren Williams, who finished ...