Researchers have developed an optogenetics platform that enables precise spatiotemporal control over the storage and release ...

A KAIST research team led by Professor Won Do Heo (Department of Biological Sciences) has developed an optogenetic platform, ...

A KAIST research team led by Professor Won Do Heo (Department of Biological Sciences) has developed an optogenetic platform, ...

Next steps Moving forward, the team envisions extending their AI strategy to encompass protein-RNA interactions, an area where reliable AI approaches for high-quality protein-RNA complex structure ...

Segovia and Krainer were particularly interested in SRSF1's interaction with a protein called DDX23. This enzyme helps newly built spliceosomes get themselves into shape for RNA splicing.

More information: Jiangle Liu et al, RNA codon expansion via programmable pseudouridine editing and decoding, Nature (2025). DOI: 10.1038/s41586-025-09165-x Provided by Peking University ...

They found many were RNA-binding proteins (RBPs), in keeping with their involvement in pathogenic protein aggregation and their known interactions with tau (May 2016 news; reviewed by Maziuk et al., ...

In humans and fruit flies alike, RNA editing prevents autoimmune responses and adjusts protein functions. However, in humans, most editing occurs in non-coding regions, with only a small fraction ...