This study highlights the promising potential of LC–MS as a powerful tool for mAb quality control within the context of upstream processing.

The FDA has granted approval to Akeso's differentiated programmed cell death protein 1 (PD-1) monoclonal antibody, penpulimab ...

The increased stability from combining these proteins allowed the group to successfully generate monoclonal antibodies. The investigators determined which antibody was best able to specifically ...

NU-9 targets a shared underlying mechanism found in various neurodegenerative diseases. A new study from Northwestern ...

Animal testing requirements for monoclonal antibodies and other medications will be “reduced, refined or potentially replaced ...

Another reason for choosing a particular modality is that it is a team’s specialty. Strategic choices can be less about determining which modality best fits a potential target than about choosing a ...

The FDA is moving away from requiring animal models for investigational new drug (IND) applications for new monoclonal antibodies and ... human organ model-based lab testing and real-world human ...

Antibodies are best known for their ability to latch onto and neutralize bacteria, viruses and other pathogens. But these ...

Abnormal kinase signaling can promote other harmful traits, such as neuroinflammation and neuronal cell death. On the other ...

The most potent of the new antibodies was found to provide protection against malaria parasites in an animal model. The researchers ... Anti-malarial monoclonal antibodies (mAbs) are another ...