Enrollment on track in Phase 2 pivotal portion of PYNNACLE clinical trial evaluating rezatapopt as monotherapy in patients with TP53 Y220C and KRAS wild-type advanced solid tumorsInterim analysis from ...

PMV Pharma ended the first quarter with $165.8 million in cash, cash equivalents, and marketable securities, compared to $183.3 million as of December 31, 2024. Net cash used in operations was $18.3 ...

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...

Soft tissue sarcoma is a type of cancerous tumor that forms in the body’s soft tissues, such as muscle, fat, fibrous tissue, and blood vessels. If it occurs in the shoulder, it might feel like a ...

Loss of the tumor suppressor p53 facilitates the malignant progression of colorectal cancer (CRC) following the initial transformation. Here, the authors report that p53 protein degradation ...

The work shows that the AGO2 protein follows the tumor suppressor p53 into the nucleus, binding itself to genes that regulate the body's alarm signals and turning them off. The researchers also ...

State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education ...

For exclusive news and updates, subscribe to our The Bold and the Beautiful Newsletter: The Bold and the Beautiful‘s Liam Spencer has been diagnosed with an inoperable brain tumor, which means ...