Novel cancer therapy combining multi-hydroxylated fullerene (MF) nanoparticles and mTOR inhibitors triggers organelle cascade ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Researchers from Aarhus University and Synuca Therapeutics recently presented a novel drug-like small-molecule inhibitor of sarco/endoplasmic reticulum calcium ATPase (SERCA), SYN-4569, with superior ...

As De Camilli and collaborators have previously shown, the VPS13C protein acts as a bridge that transfers lipids from the ...

School of Chemistry, Key Laboratory of Advanced Technologies of Material, Ministry of Education, School of Life Science and Engineering, Southwest Jiaotong University, Chengdu 610031, People’s ...

In lab-grown nerve cells from ALS patients, the compound helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.

n lab-grown nerve cells from ALS patients, the compound helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.

Wang made the remarks in an interview with China Science Daily on March 28. The endoplasmic reticulum is often termed the cellular “highway” that links sub-cellular structures such as the ...

Endoplasmic reticulum stress (ERS) was essential in promoting EMT advancement in fibrotic diseases and cancers. Upon ERS initiation, protein kinase R (PKR)-like ER kinase (PERK) was activated, causing ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes ...