The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

Cells have extensive sets of intracellular membranes, which together compose the endomembrane system. The endomembrane system was first discovered in the late 1800s when scientist Camillo Golgi ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions—as enzymes ...

Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization ...

Thomas Ostwald and David MacLennan were characterizing proteins that bind to calcium in the sarcoplasmic reticulum — a specialized type of endoplasmic reticulum found in muscle cells.

As De Camilli and collaborators have previously shown, the VPS13C protein acts as a bridge that transfers lipids from the ...

Wang made the remarks in an interview with China Science Daily on March 28. The endoplasmic reticulum is often termed the cellular “highway” that links sub-cellular structures such as the ...

Novel cancer therapy combining multi-hydroxylated fullerene (MF) nanoparticles and mTOR inhibitors triggers organelle cascade ...

In lab-grown nerve cells from ALS patients, the compound helped the cells produce more energy and eased stress in the protein-processing center of the cell called the endoplasmic reticulum.

We explore endoplasmic reticulum homeostasis, protein aggregates, neural development, and glial cells—all essential players in brain health and disease. At the heart of our mission is a passion for ...