Unlike bacterial cyclic dinucleotides, cGAMP produced by cGAS is formed by an unusual combination of one conventional 3′ to 5′ phosphodiester bond, similar to the bonds found in DNA and RNA ...

James Watson and Francis Crick revealed the structure of DNA — the genetic instructions in all living things — 70 years ago in the journal Nature. Watson and Crick could not have succeeded ...

DNA is made up of adenine-thymine (AT) bonds and guanine-cytosine (GC) bonds. The frequency of each type of bond differs substantially across bacterial species. A new study uses this quirk of ...