Such probes are sensitive, even to single base differences in target DNA. Freed from the constraint of needing hydrogen bonding to achieve rapid, high-fidelity DNA synthesis, one may be able to ...

In this type of pairing, adenine (A) forms two hydrogen bonds with thymine (T) in DNA or uracil (U) in RNA, while guanine (G) forms three hydrogen bonds with cytosine (C). These base pairs are highly ...

DNA is made up of adenine-thymine (AT) bonds and guanine-cytosine (GC) bonds. The frequency of each type of bond differs substantially across bacterial species. A new study uses this quirk of ...

First, a so-called initiator protein unwinds a short stretch of the DNA double helix. Then, a protein known as helicase attaches to and breaks apart the hydrogen bonds between the bases on the DNA ...

an energy currency that can be scarce—so instead of covalent bonds, which are more permanent because they require more energy to sunder, DNA strands are held together by delicate hydrogen bonds ...

Hydrogen bonds are the invisible forces that hold water molecules together, giving water its unique properties, from high boiling point to surface tension, and enabling critical biological functions ...

In the double helix structure of DNA, thymine forms a base pair with adenine through two hydrogen bonds. This specific pairing is known as complementary base pairing and is essential for the stability ...

and enabling critical biological functions such as protein folding and DNA structure. Yet despite their significance, quantifying hydrogen bonds in complex or confined environments has long been a ...