The research team designed and tested a library of lipids to optimize their ability to cross the blood-brain barrier. Through ...

Vect-Horus has a clinical-phase solution to a key drug development challenge: crossing the blood–brain barrier (BBB ... that other companies use to cross the BBB. The weight difference ...

A harmful form of the tau protein, which builds up in Alzheimer's disease and similar brain disorders, can directly damage ...

Overall, we accounted for more than 95% of the variability in the data from drugs that cross the blood-brain barrier by passive diffusion." The study also looked at those compounds that do not go ...

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions ...

A common gastrointestinal cancer drug that crosses the blood-brain barrier showed promise in patients with aggressive high-grade gliomas. Paige is pursuing a PhD in neuroscience at the University of ...

But research is starting to reveal multiple potential causes from inflammation to a leaky blood-brain barrier. Difficulty concentrating, forgetfulness, confusion, and cognitive slowness or ...

The properties of the blood-brain barrier serve a vital protective role, but they also keep drugs from reaching the organ. Big pharmaceutical companies have been making deals for technologies that ...

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, ...

Getting therapeutic drugs past the blood-brain barrier has long been a major challenge in treating brain diseases. Now, researchers have explored how cholesterol-modified heteroduplex oligonucleotides ...

Furthermore, docetaxel (the drug of choice for the first-line treatment of castration-resistant PC) cannot cross the blood–brain barrier and control metastatic foci. However, this problem may be ...