This results in the formation of two large molecular complexes, the pre-60S and the pre-40S subunits. Both are then passed through the nuclear pores into the cell, where they are assembled in a ...

These grippers limit the speed at which the subunits can get past the nuclear membrane. The study indicated that pre-60s subunits accumulate right where the gripping protein moves the subunits through ...

All proteins in a cell are assembled by complicated molecular machines. The precursors of these ribosomes are produced in the cell nucleus and then enter the cell through the so-called nuclear pores.

In yeast, the smaller 40S subunit is derived from a much larger precursor complex called the 90S pre-ribosome. The 90S precursor particle contains a single (35S) RNA molecule.

Maturation of the ribosome is a complex operation. Work by an Ludwig-Maximilians-Universitaet (LMU) in Munich team now shows that the 90S precursor of the small 40S subunit undergoes a 'molting ...