The blood-brain barrier border protects the brain by regulating the flow of molecules, peptides, and cells, but it also keeps ...

REAL AD hints that blood markers can spot subtle cognitive decline. People who fluff a digital cognitive test have more ...

Conference after conference, Roche scientists running the ongoing Brain Shuttle AD trial of trontinemab are dispensing ...

Alzforum webpages for each DIAN-TU-eligible variant now state “DIAN-TU eligibility: Yes” near the top of the page and an ...

For years, scientists have been working toward blood tests for Alzheimer’s disease that could be used routinely in clinical practice. Now, they are on the cusp. At this year’s ADPD conference, held ...

Scientists see several important uses for staging. For example, it can steer people more precisely to appropriate treatments.

For one, microglia hovering around plaques—the type that express the most TREM2—reportedly become desensitized to stimulation ...

Space, An Early Frontier. When a brain region is tau-negative by SUVR (green arrow, left), spatial extent (dark blue) correlates better with measures of disease severity than does SUVR (light blue).

Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...