Background The integration of artificial intelligence (AI) into critical care offers significant potential to enhance early diagnosis, predict patient deterioration, personalise treatment and inform ...

Objectives Recent falls in CF admissions have been attributed to reduced exacerbations (PEx) in patients on CFTR modulators. We aimed to understand how these have affected the presentation and course ...

COPD is set to become the third leading cause of death globally by 2023. To date, we have no significant disease modifying therapies. COPD patients experience chronic inflammation and defective innate ...

Background Increased expression of TRPV1 receptors in the airways of chronic cough patients and heightened cough responses to inhaled capsaicin are suggestive of a role for TRPV1 receptors in chronic ...

Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, Arizona, USA Correspondence to Dr S Guerra, Arizona Respiratory Center, University of Arizona, 1501 N. Campbell Ave, PO ...

5 The Research Center of Experimental Medicine, Guangzhou Medical University, Guangzhou, Guangdong, China 6 The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China 7 ...

Chronic cough (CC) is common, predominantly affecting middle-aged females. Sufferers experience significantly impaired quality of life (QoL). Cough is associated with increased healthcare costs.

Objective: A study was undertaken to estimate the cost-effectiveness of using continuous positive airway pressure (CPAP) in the management of patients with severe obstructive sleep apnoea/hypopnoea ...

Rationale While cross-sectional studies have shown associations between certain occupational exposures and lower levels of lung function, there was little evidence from population-based studies with ...

Background: Mannose-binding lectin (MBL) deficiency has been associated with infections of the respiratory tract and with increased disease severity in cystic fibrosis (CF). The mechanism is uncertain ...

1 Real World Data Science, Medical Evidence, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK 2 Respiratory Evidence Strategy, BioPharmaceuticals Medical, AstraZeneca, Cambridge, UK 3 Research ...

Background The aim of this study was to estimate the long-term (cost-) effectiveness of smoking cessation interventions for patients with chronic obstructive pulmonary disease (COPD). Methods A ...