Understanding the neural mechanisms underlying associative threat learning is essential for advancing behavioral models of threat and adaptation. We investigated distinct activation patterns across ...

See more details Toxoplasma gondii replicates through endodyogeny, an unconventional form of internal budding in which two daughter cells are assembled within a single mother cell. During this process ...

Neurons selective to running trajectories in the rat anterior cingulate cortex are reactivated during observation and interact with hippocampal replay to guide subsequent spatial navigation.

Intrinsically disordered regions in transcription factors enhance both target binding probability and search efficiency.

This study addresses an important question and shows how social navigation in homing pigeons can be explained by simple averaging, without requiring any complex cognitive abilities. The evidence, ...

Fibronectin triggers secretion of extracellular vesicles carrying collagen VI that regulate smooth muscle cell adhesion and migration during vascular repair and atherogenesis.

Rapamycin, competing with other rapalogs, activates TRPM8 via directly binding to a novel binding site, which results in providing new insights into the mechanisms of TRPM8 activation.

A study of 28 hoverfly species suggests that smaller insects compensate for their size by evolving proportionally longer and more force-efficient wings, rather than changing how they flap.

A novel compound that inhibits the BAF chromatin remodeling complex causes regression in an animal model of the incurable cancer uveal melanoma.

This important study demonstrates that ocular organoids can generate both retina and lens through a non-canonical, "inside-out" morphogenetic route. The work is solid, with well-designed experiments ...

Structural and computational approaches uncover the molecular basis for dimerization, open-closed conformational transitions, and the dynamic behavior of the human angiotensin-I converting enzyme ...

To parse foreground and background sounds, the auditory cortex of humans and ferrets share a similar hierarchical organization, but the underlying computational mechanisms are fundamentally different.