The Detroit Lions’ rebuild was jumpstarted by the fact that the first pick of the Brad Holmes and Dan Campbell, which was ...

The Detroit Lions visit the San Francisco 49ers on Monday at 8:15 p.m. ET, in a matchup featuring a pair of the best ...

If the Minnesota Vikings win, then this game will not have an impact on the Lions' ability to clinch. However, a Vikings loss ...

All three Saturday games on the Week 17 NFL schedule will have a significant impact on the NFL postseason. The Los Angeles ...

For Lions defensive coordinator Aaron Glenn's money, 49ers star George Kittle is the best tight end in football.

SportsLine expert Eric Cohen reveals his score predictions for the 14 remaining games in Week 17 of the NFL schedule ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

The Lions will face a 49ers offensive line that could be starting two tackles signed off practice squads this week ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

Find out what the San Francisco 49ers are saying as they prepare for their Week 17 matchup vs. the Detroit Lions.

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

Mike Spofford and Wes Hodkiewicz break down the keys to the game as the Green Bay Packers face off against the Minnesota Vikings in an NFC North matchup at U.S. Bank Stadium.