So, what is the reason behind San Francisco's inability to stay healthy? Is there a deeper problem here? Well, Matt Barrows of The Athletic identified what he feels is the reason for the Niners' constant injury problems,

Locked into long-term contracts, Brock Purdy, Kyle Shanahan, and John Lynch give the 49ers stability, but their trajectory depends on developing young talent around an aging core and maintaining championship-level coaching.

NFL insider Dianna Russini reported the San Francisco 49ers are “making calls” in pursuit of a trade for a wide receiver.

On Wednesday, 49ers head coach Kyle Shanahan told KNBR radio that Robinson has been suspended for the first three games of the 2025 NFL season for violating the league’s substance abuse policy, per ESPN’s Adam Schefter.

Add the New York Jets and San Francisco 49ers to the list of NFL teams scrambling to trade for a wide receiver before the final roster cut-down.

Robinson signed a two-year, $9.5 million contract with the 49ers back in March after a two-year stint with the NFC West rival Los Angeles Rams. In his eight-year NFL career, which also included stops with the Kansas City Chiefs and Baltimore Ravens, Robinson has averaged 31 catches, 376 yards, and three touchdowns per season.

Trade: Chiefs are sending WR Skyy Moore to the San Francisco 49ers. The 49ers have been decimated with injuries at WR. Brandon Aiyuk is recovering from a knee injury, Jauan Jennings has been dealing with a calf injury, Jordan Watkins has a high ankle sprain, DeMarcus Robinson is… pic.twitter.com/Yb6SDVY9VS

The 49ers have a lot of concerns at the wide receiver position ahead of the 2025 season, and Demarcus Robinson's suspension just complicated things more.

San Francisco 49ers wide receiver Brandon Aiyuk is likely itching to get back on the field after suffering a season-ending injury in Week 7 last season, but he and the team may have broken an NFL rule as he works his way back from a torn ACL and MCL.