The San Francisco 49ers had huge plays on both sides of the ball to earn a blowout win over the Arizona Cardinals. Here are the highlights.

Jacoby Brissett completed an NFL-record 47 passes, but San Francisco's offense rolled in Purdy's first game in weeks.

Cardinals 41-22 in Week 11. Key stats, record milestones, and standout performances from Purdy, McCaffrey, Kittle, and the defense.

Brock Purdy’s return went perfectly on Sunday afternoon. The San Francisco 49ers quarterback started after missing six straight games due to a toe injury, and he had no issue leading the 49ers to a commanding 41-22 win over the Arizona Cardinals. Purdy went 19-of-26 passing for 200 yards with 3 touchdowns.

The San Francisco 49ers are already without Fred Warner, and they may have lost another linebacker early against the Arizona Cardinals on Sunday.

When San Francisco 49ers head coach Kyle Shanahan spoke at the podium after last week's game, he had no injuries to report—a rare moment for one of the NFL's most frequently banged-up teams. Unfortunately, that wasn't the case after Sunday's 41-22 victory over the Arizona...

Brock Purdy returned from a six-game absence to throw three touchdowns as the 49ers (7-4) romped to a 41-22 win over the host Cardinals (3-7).

San Francisco 49ers' QB Brock Purdy discusses his return from injury and three touchdown performance against the Arizona Cardinals.