Watch the best plays from Buffalo Bills running back James Cook during Week 4 of the 2025 NFL season against the New Orleans Saints.

Highlights from the Week 4 matchup between the New Orleans Saints and the Buffalo Bills during the 2025 NFL season.

The New Orleans Saints dropped to 0-4 on the season after a 31-19 loss to the Buffalo Bills. Despite an early back-and-forth ...

The Bills (4-0) kept their winning ways going in Week 4 against the New Orleans Saints (0-4) in a 31-19 final. While a win, Buffalo kept a bit of a tradition going. The Bills allowed the Saints to ...

ORCHARD PARK, N.Y. (KPLC) - The New Orleans Saints travel to Highmark Stadium to take on the Buffalo Bills for Week 4 of the ...

The Bills and Saints play Sunday in Week 4 of the 2025 NFL season.

ORCHARD PARK, N.Y. (WVUE) - The New Orleans Saints made it interesting in the fourth quarter (trailing 21-19), but couldn’t ...

Josh Allen threw two touchdown passes and ran for a score, and the Buffalo Bills shook off a sloppy first three quarters to stay undefeated, beating the winless New Orleans Saints 31-19.

Week 4 in the NFL was kind to some quarterbacks, and brutal to others. As is the case each and every week, signal-callers are under the microscope. Unless your ...

The New Orleans Saints fall to 0-4 to open the 2025 season after suffering a defeat in Buffalo against the powerful Bills.The final score Sunday afternoon 31-19.The Black & Gold are now 0-4 to open a ...

The Buffalo Bills remained unbeaten with a 31-19 win over the New Orleans Saints on Sunday at Highmark Stadium in Orchard ...

Saints receiver Chris Olave caught a 3-yard touchdown pass in the third quarter but the two-point attempt failed to make it 21-16. Grupe's second field goal made it 21-19 but Buffalo immediately ...