New Orleans Saints battle back in loss to Buffalo Bills
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The New Orleans Saints dropped to 0-4 on the season after suffering a loss to the Buffalo Bills in Week 4, but it wasn't as lopsided of a game as many expected
New Orleans Saints head coach Kellen Moore speaks with the media from the Ochsner Sports Performance Center on Monday, September 29, 2025 the day after the Saints' Week 4 game against the Buffalo Bills and ahead of Week 5 against the New York Giants.
The Bills committed 11 penalties but pulled away in the fourth quarter to beat the Saints. Here are the highlights.
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QB Josh Allen leads Bills to 4-0 start, but concerns linger after close call in win over Saints
High expectations have their price, leaving Josh Allen and the Buffalo Bills unhappy, but relieved, following a close call against the winless New Orleans Saints.
New Orleans Saints running back Kendre Miller speaks with the media from the Ochsner Sports Performance Center on Monday, September 29, 2025 the day after the Saints' Week 4 game against the Buffalo Bills and ahead of Week 5 against the New York Giants.
Buffalo is a 14.5-point favorite in the latest Saints vs. Bills odds from SportsLine consensus, while the over/under for total points scored is 48. The Bills are -1562 money line favorites (risk $1,562 to win $100),
Expert recap and game analysis of the Buffalo Bills vs. New Orleans Saints NFL game from September 28, 2025 on ESPN.
Here are your Five Things to Know about the New Orleans Saints for Monday, September 29: 1. The New Orleans Saints fell in a 31-19 loss in Week 4 against the Buffalo Bills. Catch up on all the action, stats and reactions in our Game Center at NewOrleansSaints.com.