As the translation machinery carouses along the string of nucleotides that make up the mRNA, it recognizes them in groups of three, called codons. Each codon corresponds to a specific amino acid.

This means adults have a choice in which COVID vaccine they receive: an mRNA vaccine by Moderna or Pfizer, or Novavax, a protein-based vaccine that targets the virus in a more "traditional" way.

Eukaryotic mRNA cap structures directly influence mRNA stability, translation, and immune recognition. While the significance of the mRNA cap itself has been well-established, recent research has ...

We related mRNA to protein statistically using best-available data from quantitative proteomics and transcriptomics for 4366 genes in 369 cell lines. The approach starts with a protein’s median copy ...

N6-methyladenosine (m6A) is considered the most prevalent methylation modification in messenger RNA (mRNA) that critically impacts head and neck cancer (HNC) pathogenesis and development. Alterations ...

aDepartment of Rheumatology and Immunology, Hannover Medical School, Hannover 30625, Germany bDepartment of Pediatric Pulmonology, Allergology, and Neonatology, Hannover Medical School, Hannover 30625 ...

As a reminder, in addition to the current COVID-19 vaccine, the company is actively working on a next-generation vaccine (mRNA-1283). According to phase 3 trial data (NEXTCove), the vaccine's ...

Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers. The investigational mRNA cancer immunotherapy ...

m6A is the most widespread mRNA modification and is primarily implicated in controlling mRNA stability. Fundamental questions pertaining to m6A are the extent to which it is dynamically modulated ...

As the translation machinery carouses along the string of nucleotides that make up the mRNA, it recognises them in groups of three, called codons. Each codon corresponds to a specific amino acid.