On Sunday at 8:20 p.m. ET, Khalil Shakir and the Buffalo Bills play the New England Patriots in Week 5. Game Time: 8:20 p.m.

Cole Bishop made an athletic interception on Chris Olave's attempted pass to Spencer Rattler, thwarting New Orleans' attempt ...

The Buffalo Bills have done what they've needed to do to win, but that hasn't come without a fair share of concerns on both sides of the ball.

The Philadelphia Eagles used a fake tush push, another special teams touchdown and a late defensive stop to stay undefeated.

Buffalo’s defense secured the win in the final minutes. Following Kincaid’s TD, the Saints turned the ball over on downs at midfield when Alvin Kamara was stopped for a 2-yard gain by Tre’Davious ...

It wasn’t always pretty, but the Bills came away with a hard-fought 31-19 win over the New Orleans Saints to improve to 4-0 on the season. Buffalo was in danger ...

Saints rookie safety Jonas Sanker had three pass breakups and his first career interception Sunday against reigning MVP Josh ...

Khalil Shakir put the Buffalo Bills on the board first against the New Orleans Saints, and the TD could be in contention for the Play of the Year.

Buffalo Bills wide receiver Khalil Shakir scores a touchdown on a 43-yard reception against the New Orleans Saints during ...

The Bills are heavily favored in their Sunday matchup with the Saints. Stay tuned for live updates throughout the day.

In what's expected to be one of the biggest lopsided matchups of Week 4, it did not take the Bills long to take an early lead ...

The Bills committed 11 penalties but pulled away in the fourth quarter to beat the Saints. Here are the highlights.