He joins Brandon Aiyuk who was ruled out with a knee injury. Third quarter update: The team announced that Samuel is questionable to return with his illness, per Cam Inman. Second quarter update: Samuel is headed back to the locker room three minutes before halftime,

The 49ers’ already depleted offense took a hit on Sunday as Brandon Aiyuk and Deebo Samuel were deemed out for the second half

Deebo Samuel needed an oxygen mask to help deal with an illness he picked up before the Chiefs game in the first quarter.