This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.

Pupil dilation provides a physiological readout of information gain during the brain's internal process of belief updating in the context of associative learning.

1 British Heart Foundation National Centre for Physical Activity and Health, School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK 2 School of Population Health, ...