The 49ers running game has been up and down, but they could have an advantage against a very solid Colts run defense ...

The Indianapolis Colts ruled out cornerback Sauce Gardner ahead of Monday Night Football. It’s not often that the San ...

Colts cornerback Charvarius Ward is in concussion protocol after reporting symptoms following the team's loss to the Jaguars.

This was Purdy at his dart-throwing best, completing 25 of 34 passes for 295 yards and five touchdowns, the first time any ...

All 3 phases, we lost today.' Franklin's wrong. Colts were gashed in the middle of the field, gave up 440 yards, 41 points ...

The San Francisco 49ers, on a four-game winning streak, try to stay hot Monday night against an Indianapolis Colts team on a ...

It all started on the kickoff after the 49ers scored their first touchdown of the game. Ameer Abdullah caught the ball, ran ...

The Colts lose starting cornerback Charvarius Ward to IR and announce the signing of quarterback Philip Rivers. More at Pro Football Rumors.

The Colts desperately need a win in Week 16 against the 49ers. Here are 3 Colts bold predictions before their huge MNF game.

According to Adam Schefter, Colts CB Charvarius Ward has no plans to retire despite being placed on injured reserve with his third concussion of the season ...

The Colts defense ruined QB Philip Rivers' fabulous game, letting the 49ers win a Monday Night rout that all but cancels the ...

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats and more for Colts-49ers.