The San Francisco 49ers took potentially more than one loss against the Kansas City Chiefs. All-Pro wide receiver Brandon ...

The 49ers’ already depleted offense took a hit on Sunday as Brandon Aiyuk and Deebo Samuel were deemed out for the second ...

San Francisco 49ers wide receiver Brandon Aiyuk exited Sunday's loss against the Kansas City Chiefs during the first half ...

San Francisco 49ers head coach Kyle Shanahan discusses Sunday’s 28-18 loss to the Kansas City Chiefs, believes that Brandon ...

Brandon Aiyuk was carted off from the sideline before halftime Sunday. Aiyuk was injured with 37 seconds left in the half ...

The last time star wide receiver Brandon Aiyuk and the San Francisco 49ers took on the Kansas City Chiefs, it did not go ...

The San Francisco 49ers lost standout receivers Brandon Aiyuk and Deebo Samuel during Sunday's 28-18 loss to the visiting ...

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, but they may have lost a ...

San Francisco 49ers wide receiver Brandon Aiyuk might have suffered a significant injury in Sunday's loss to the Kansas City ...

Chiefs defenders Justin Reid and Chamarri Conner sandwiched the receiver on a tackle in the waning seconds of the first half.

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on ...

Already missing one of their top three receivers, the 49ers ruled out Brandon Aiyuk (knee) and Deebo Samuel (illness) for the ...