It may not be quite time to push the panic button in San Francisco, but perhaps it's time to start thinking about it. The ...

Other stars, including Cleveland's Deshaun Watson, Washington's Jayden Daniels and San Francisco's Brandon Ayiuk all left ...

Nothing about this San Francisco 49ers season has gone according to plan, but Brandon Aiyuk's injury may have been the low ...

The 49ers are 3-4 and have been dealing with injuries all season. They could strike a trade to help save the season.

Latest injury update on Brandon Aiyuk, who injured his leg and was carted off during the 49ers' game against the Chiefs on ...

The Aiyuk injury leaves the 49ers woefully short on wide receivers. Rookies Ricky Pearsall and Jacob Cowing were on the field ...

The San Francisco 49ers lost their Super Bowl rematch to the Kansas City Chiefs on Sunday, 28-18, but they may have lost a ...

Brandon Aiyuk was carted off at the end of the first half against the Chiefs after a crunching tackle messed up his leg.

The last time star wide receiver Brandon Aiyuk and the San Francisco 49ers took on the Kansas City Chiefs, it did not go ...

The San Francisco 49ers took potentially more than one loss against the Kansas City Chiefs. All-Pro wide receiver Brandon ...

The San Francisco 49ers lost standout receivers Brandon Aiyuk and Deebo Samuel during Sunday's 28-18 loss to the visiting ...

San Francisco 49ers rookie receiver Ricky Pearsall made his NFL debut exactly 50 days after being shot in the chest during a ...