Yang, Chen et al. present ModVAR, a multimodal tool that integrates DNA sequence, protein structure, and cancer omics to predict cancer driver variants. It performs strongly on validated benchmarks, ...
Protein kinases comprise one of the largest families of evolutionarily related proteins. Mutations in kinase genes underlie many human diseases, particularly developmental and metabolic disorders, as ...
Epidermal growth factor receptor (EGFR) is a protein on the surface of your cells that helps them grow. When the gene that codes for EGFR has a mutation, it affects the way this protein works, causing ...
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