Researchers at Bar-Ilan University reveal protein changes linked to longevity throughout mammalian evolution. Over the past ...

These protein modifications allow our bodies to regulate certain processes—or stop them entirely. MDA5 is a protein involved in the very first step of how human bodies detect viruses.

Cleveland Clinic virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how human bodies detect and respond to viruses and viral replication.

The modification of a protein can enhance or change the role of the protein. For instance, when a protein is phosphorylated, it might become an active enzyme, be targeted to a subcellular ...

These protein modifications allow our bodies to regulate certain processes – or stop them entirely. MDA5 is a protein involved in the very first step of how human bodies detect viruses.

Functional cysteine residues demonstrate heightened reactivity relative to non-functional cysteines, and are sensitive to a myriad of oxidative protein modifications that serve to regulate protein ...

As workers in proteomics, mass spectrometry and bioinformatics, acting with others to develop and promote standards for storing data, and submitting and publishing results, we propose a community ...

This 7-day plan is set at 1,500 calories per day, with modifications for 1,800 and 2,000 calories per day. Each day provides ...

Sudden environmental changes near the protein, like varying temperature, pH, shear force, or chemical modification, can cause conformational alterations within the protein. These changes in ...

Get Instant Summarized Text (Gist) Modification of the immune protein MDA5 is crucial for detecting viruses and limiting viral replication, which helps prevent virus-induced heart inflammation ...

The PNASpublication explains how two protein modifications activate MDA5, an essential immune protein, to sense invaders, limit viral replication and fight infections.This process is key to ...