Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...

Colorectal cancer is the third most diagnosed type of cancer worldwide. Up to 80% of the cases are related to environmental ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...

PMV Pharma ended the first quarter with $165.8 million in cash, cash equivalents, and marketable securities, compared to $183.3 million as of December 31, 2024. Net cash used in operations was $18.3 ...

Enrollment on track in Phase 2 pivotal portion of PYNNACLE clinical trial evaluating rezatapopt as monotherapy in patients with TP53 Y220C and KRAS wild-type advanced solid tumorsInterim analysis from ...

Loss of the tumor suppressor p53 facilitates the malignant progression of colorectal cancer (CRC) following the initial transformation. Here, the authors report that p53 protein degradation ...

Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key ...

A hidden clue may explain why some mutated cells become cancerous and others don’t: how fast they divide. A new study from ...

The work shows that the AGO2 protein follows the tumor suppressor p53 into the nucleus, binding itself to genes that regulate the body's alarm signals and turning them off. The researchers also ...

The influenza virus manipulates the body's gene regulation system to accelerate its own spread. A new study also shows that an already approved drug could help strengthen immune defenses -- though its ...