Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations—referred ...

A scientific revolution is underway as researchers push to bring atomic-level precision, once reserved for small molecule ...

Historically, small molecule drugs have been precisely designed down to the atomic scale. Considering their relatively large complex structures, nanomedicines have lagged behind. Researchers argue ...

Structural biology is the study of the molecular structure and dynamics of biological macromolecules, particularly proteins and nucleic acids, and how alterations in their structures affect their ...

In 2015, a 7.8 earthquake hit Nepal, killing nearly 9,000 and injuring thousands. The earthquake resulted in losses exceeding ...

Historically, the vast majority of pharmaceutical drugs have been meticulously designed down to the atomic level.

Certain DNA sequences can form structures other than the canonical double helix. These alternative DNA conformations - ...

The preclinical study, published April 17 in Nucleic Acids Research, brings us closer to understanding ... But if that doesn't happen properly, repair enzymes could mistake the structure for a break ...

In the final ELVIS platform delivered to orbit, the DHM module "provides better than 0.8-micron spatial resolution across a 0.25 mm 3 flow-through cell, and has the ability to detect fewer than 100 ...

Single-cell RNA sequencing (scRNA-seq) has confirmed that MM exhibits high intra-tumor heterogeneity, comprising a mixture of ...

The role of insects in drug discovery is expanding, with biopharmaceuticals derived from insect cells offering sustainable solutions for medical applications.