This protocol presents a tripartite mammalian cell-free translation system, comprising cytoplasmic and ribosome fractions combined with endogenous or synthetic mRNAs, permitting flexible ...

Where mRNAs are localized in a fully grown mammalian oocyte has been a longstanding question ... These molecules cluster around mitochondria throughout the cytoplasm, forming a structure the team ...

The crystal structure of the universal ribonucleoprotein ... SRP was first identified in mammalian cells in the early 1980s as a soluble complex of six polypeptides and a 300 nucleotide RNA ...

Recently, his group also obtained a breakthrough in visualizing mammalian mitochondrial ribosomes with their high-resolution cry electron microscopic study that revealed its unusual structure and the ...

The process of translation by ribosomes, which functions as a factory of protein synthesis, may be impeded by ‘ribosome ...

Proteins form the structural and functional backbone of the cell, and any perturbation in their synthesis can disrupt normal ...