Major depressive disorder (MDD) is a leading cause of disability worldwide, with a significant proportion of patients (10-20%) progressing to treatment-resistant depression (TRD).

IntroductionMajor depressive disorder (MDD) is a leading cause of disability worldwide, with a significant proportion of patients (10-20%) progressing ...

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic.

Ketamine, a non-competitive N-methyl-D-aspartate receptor antagonist, has emerged as an effective therapeutic agent for the management of treatment-resistant depression. Repeated treatments with ...

The anesthetic ketamine is being hailed as a breakthrough therapy for people with post-traumatic stress disorder (PTSD), ...

Ketamine also has come under increasing scrutiny as a treatment recently, with studies suggesting that for some patients it ...

A Hollywood Tragedy,' which focuses on a criminal investigation and charges brought after the actor’s death in October 2023.

New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D.

Jeff Winograd, who's lived with depression for more than 25 years, says ketamine treatment saved his life. Jeff Winograd couldn’t get off his couch. He’d hit rock bottom with the depression he ...