The induced interaction results in ubiquitination and subsequent degradation of the recruited protein. Through this mechanism of action molecular glues are not restricted to the agonistic/antagonistic ...

The induced interaction results in ubiquitination and subsequent degradation of the recruited protein. Through this mechanism of action molecular glues are not restricted to the agonistic ...

SHP2 inhibition could be an ideal way to treat certain cancers, and degradation of the protein is one of the promising approaches. Allosteric inhibition is currently preferable for SHP2 because of ...

“We are excited to share this data on superior degradation efficacy against KRAS G12D, a long-targeted oncogene, with the scientific community at the AACR Annual Meeting, and grateful to SEED ...

KING OF PRUSSIA, Pa. , April 24, 2025 (GLOBE NEWSWIRE) -- SEED Therapeutics Inc. (“SEED”), a biotechnology company pioneering the discovery of molecular glues for targeted protein degradation ...