Researchers developed cSMRTS, an engineered mRNA that preferentially turns on therapeutic genes inside targeted cells, shown ...

Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells-an advance ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed ...

Transposable elements are stretches of DNA that can move around the genome. Many of these DNA sequences originate from long ...

Explore how the future of obesity drugs starts in preclinical discovery, addressing global challenges and advancing treatment ...

CAG repeats can get longer over time as the HD gene is used, like the growing potholes and cracks in an old road. New ...

A newly discovered organism is challenging the fundamental definition of life, blurring the lines between viruses and ...

Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to ...

A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...

A team led by Rensselaer Polytechnic Institute (RPI) professors Georges Belfort, Ph.D. (PI), and Pankaj Karande, Ph.D. (co-PI ...

Testing in mice suggests that rejuvenating T cells could make vaccines and some cancer therapies more effective.

RNA vaccines, such as those used against COVID-19, are effective at generating antibody responses. These antibodies are ...