The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

A 28-year-old woman was admitted to the hospital because of severe hypoxemia and right heart failure that had been caused by rapidly progressive pulmonary hypertension. A diagnosis was made.

A man from rural India presented with redness and blurry vision in one eye. Examination was notable for panuveitis and a live worm in the posterior segment; the worm was removed in a pars plana vit ...

Though infant mortality has continuously been targeted by health policy agendas, policies tend to place it in an individualistic and narrow frame, failing to consider and address its structural ...

To prevent the spread of inaccurate information, academic and health care institutions will need to equip scientists and clinicians to engage effectively on nontraditional media platforms.

An industry-supported center claims that it costs companies $2.6 billion to develop a new drug. But we need a broader-based and more transparent reckoning of research-and-development costs to infor ...

A small-molecule drug proves its mettle in the treatment of spinal muscular atrophy, a disease amenable to intervention at the pre-mRNA level.

A 72-year-old woman with a 30-year history of paraplegia was referred to the urology clinic for treatment of a bladder stone. CT of the abdomen revealed a large bladder stone with a tree ring ...

A 21-month-old boy presented with a pruritic rash on his left leg that was thought to be at the site of a recent insect bite. A video shows a pulsating erythematous plaque, referred to as Quincke ...

After a year of clinical rotations in which a medical student learns to face death up close, her experience on a silent meditation retreat provides her with new perspective on death and life.

The author describes the scientific foundations of a clinical trial of a first-in-class small-molecule estrogen receptor degrader to treat patients with metastatic breast cancer.

To the Editor: Gbadegesin et al. (Jan. 16 issue)1 conducted an insightful study on apolipoprotein L1 gene (APOL1) bi- and monoallelic variants and chronic kidney disease (CKD) in West Africans. Thi ...