Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src ...

Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before ...

As people age, their immune system function declines. T cell populations become smaller and can't react to pathogens as ...

T cell development is a tightly regulated process that transforms immature thymocytes into mature T cells with distinct functionalities. In the thymus, precursor cells undergo a series of selection ...

Learn how Logic-gated DARPins work to activate T cells selectively in solid tumours, enhancing therapeutic outcomes.

New data highlight liver-encoded delivery of immune modulators as a strategy to mitigate age-related immune dysfunction.

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

Automated TCR-T production streamlines personalized immunotherapy, reducing patient burden and improving engineered T cell quality.

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...