NEW YORK (Reuters) -Dual risks kept investors on edge ahead of markets reopening late on Sunday, from heightened prospects of a broad Middle East war to U.S.-wide protests against U.S. President Donald Trump that threatened more domestic chaos.

Israeli Defence Minister Israel Katz has said that Iran crossed "red lines" on Friday when its missiles targeted civilian areas in response to Israel's recent wave of attacks. "Iran has crossed red lines by daring to fire missiles at civilian population centres in Israel," he said in a statement.

Israel has escalated its ongoing conflict with Iran, striking the world's largest gas field and other energy infrastructure as part of a two-day assault that had otherwise largely targeted sites and personnel tied to the Islamic Republic's armed forces and nuclear program.

The Israeli military said, a short while ago, it has identified missiles launched from Iran toward Israel. Defensive systems are operating to intercept the threat, the military said. Upon receiving an alert,

As Israeli Prime Minister Benjamin Netanyahu vowed to fight “as long as it takes,” Iran fired missiles at Israel, and Israeli warplanes attacked air defenses around Tehran.

This is the second time President Trump and Russian President Vladimir Putin have spoken on the phone this month.

Maj. Gen. Yadlin, who flew in the 1981 Osirak reactor strike, explains why Israel's current operation against Iran represents a complex, multi-week campaign.

Israel warns "Tehran will burn" if Iran continues firing missiles, while state media say 60 people have been killed in a strike on Iran's capital.