Transcription termination in Escherichia coli is a finely tuned process that ensures precise regulation of gene expression. It involves both intrinsic and factor-dependent mechanisms. Intrinsic ...

DNA replication fork movement is impeded by collisions with transcription elongation complexes (TEC). We propose that a critical function of transcription termination factors is to prevent TEC from ...

An international collaboration between two Danish and two German teams has delineated that the so-called ‘Arsenite resistance 2 (ARS2)’ protein is capable of inducing early transcription termination ...

Small nuclear RNAs (snRNAs) are the basal components of the spliceosome and play crucial roles in splicing. Their biogenesis is spatiotemporally regulated. However, related mechanisms are still poorly ...

A bacterial protein helps to stop transcription -- the process of making RNA copies of DNA to carry out the functions of the cell -- by causing the cellular machinery that transcribes the DNA to pause ...

The protein, known as NusG, pauses the transcription machinery at specific DNA sequences to facilitate what is called "intrinsic termination" and prevent unwanted transcription that could disrupt ...

Each gene in our DNA has a beginning and an end. Defining the gene’s extremities properly is crucial to produce functional protein. A lot of research has been done on finding out what determines when, ...

Also, as the prokaryotic cell lacks a clearly defined nucleus and both transcription and translation takes place in the cytoplasm, there is no need to transport the mRNA to the cytoplasm after ...

There are a total of 5 multi-subunit complexes in the inner membrane of the mitochondria, all of which are involved in the process of oxidative phosphorylation that precedes ATP production. Of these, ...