New research bolsters the argument for extrapolating to children the data from adult studies of drugs, even for primary generalized tonic-clonic seizures (PGTC).

If first-line monotherapy with sodium valproate is unsuccessful for generalised tonic-clonic seizures, offer lamotrigine or levetiracetam as second-line monotherapy treatment. If the first choice is ...

The tonic-clonic seizures treatment market was valued at USD 34.93 billion in 2023. The market is expected to grow at a CAGR of 6% during the period 2024-2032, reaching USD 55.84 billion by 2032.

Tonic-clonic seizures These may begin with an aura — an abnormal sensation or feeling — marked by a particular smell, a feeling of vertigo, nausea, or anxiety.

Tonic-clonic seizures, also called grand mal seizures, cause violent muscle contractions and unconsciousness. Drop attacks, or atonic seizures, cause the muscles to suddenly relax, which can ...

The uncontrolled thrashing movements during a generalized tonic-clonic seizure increase the chances of injury. This type is most likely to result in a trip to the emergency room.

The Food and Drug Administration has approved Vimpat® (lacosamide) as adjunctive therapy for primary generalized tonic-clonic seizures in patients 4 years of age and older.

Data showed a clinically significant reduction in generalized tonic-clonic seizures (GTCS) and tonic-clonic seizures (TCS) from baseline in patients with developmental and epileptic ...

DENVER — Primary generalized tonic-clonic seizures present unique challenges to adolescents diagnosed with the condition, Sunita Misra, MD, PhD, said in this Healio video at the American Academy ...

“Since generalized seizures are more common in children than in adults, and since there have been very few new medications approved for use in primary generalized tonic-clonic seizures, this ...