The Trp53 gene is the most frequently mutated gene in all human cancers. Its protein product p53 is a very powerful transcription factor that can activate different biochemical pathways and affect the ...

MCM2, a component of the replicative helicase, can bind histones H3–H4 in both tetrameric and dimeric form, depending on the presence of the histone chaperone ASF1. A structural analysis of the ...

Our core provides customized MHC/peptide tetramers for identification of antigen-specific T lymphocytes by flow cytometry. Tetramers and/or their derivatives are provided for research purposes only.

NAD(H) and NADP(H) are important electron carriers in cellular metabolism that also act as essential cofactors for a range of enzymes involved in various biological processes. Nicotinamide adenine ...

The cost of making a Phycoerythrin conjugated tetramer is $800. The most expensive reagents are the biotin ligase (BirA from Avidity, LLC) and the PE-conjugated streptavidin (Prozyme). On occasion, it ...

MHC tetramers are typically prepared with most of the commonly used fluorescent labels used for flow cytometry. One major advantage of the technique is that the label is already attached to the ...

) are partnering to develop and commercialize renewable specialty chemicals, with some relevant findings already in renewable wax structures. Elevance (Lisle, IL) utilizes Nobel Prize winning olefin ...

Transthyretin can aggregate into fibrils and get deposited in the nervous system (neuropathy) and heart (cardiomyopathy). This is called transthyretin amyloidosis. Depending on whether the disease is ...

Tetramer Technologies was awarded a $12.5 million program to develop protective fabrics for soldiers. The new gear will integrate the company's Metal-Organic Framework bead technology for enhanced ...