Structural biologists including Michael G. Rossmann have obtained clearer pictures of how the T4 virus, long known to infect E. coli bacteria, alters its shape as it prepares to pierce its host's cell ...

The study may provide clues to how similar viruses infect cells and suggest ways for developing a new class of antibiotics and other drugs to prevent illnesses caused by viral pathogens. Scientists at ...

This is a close-up image of the T4 virus baseplate that the virus uses to attach to the E. coli host. The different colors represent the 16 types of proteins that form the baseplate. View Slideshow It ...

Like microscopic machine shops, some viruses assemble their parts with the help of tiny motors. Now, researchers have figured out the structure and workings of the natural molecular motors in one ...

On March 23, Catholic University announced it would be offering royalty-free licenses on patents for Rao’s work on the bacteriophage T4 virus platform and vaccine delivery systems. Prof. Venigalla Rao ...

Peering at structures only atoms across, researchers have identified the clockwork that drives a powerful virus nanomotor. Because of the motor's strength -- to scale, twice that of an automobile -- ...

Because of the motor's strength--to scale, twice that of an automobile--the new findings could inspire engineers designing sophisticated nanomachines. In addition, because a number of virus types may ...

Current calibration methods rely on artificially constructed DNA structures or specific cellular features, each with significant drawbacks. DNA-based rulers require complex chemical synthesis and only ...

WEST LAFAYETTE, Ind. - High-resolution snapshots of a virus attacking its host - which have culminated in a movie of the process - could reveal secrets of viral infection and improve gene therapy ...

WEST LAFAYETTE, Ind. — A detailed look at a syringe-like structure designed to inject viral DNA into a host cell reveals a unique and complex entry scheme for viruses. The study may provide clues to ...

credit Courtesy of Purdue University/Michael G. Rossmann laboratory and associates The T4 virus is shown here in black and white during two stages of its life cycle, before and after a portion of its ...

A detailed look at a syringe-like structure designed to inject viral DNA into a host cell reveals a unique and complex entry scheme for viruses. The study may provide clues to how similar viruses ...