Whereas early recombinant ... can also mediate Fc functions (e.g., activation of complement), since the modified antibody's Fc region displays a human amino acid sequence. Protein engineering ...

Sotatercept-csrk reduced the risk of major morbidity and mortality events in adults with WHO Group 1 PAH FC 3 or 4 at high risk of mortality.

This protein features a human IgG1 Fc tag at the N-terminus. It has a calculated molecular weight (MW) of 87.5 kDa. Due to glycosylation, it migrates at 95 kDa ± 5 kDa under reducing (R ...

We provide consultation for all projects and can assist with the design, construction, and expression testing of vectors featuring various affinity tags (i.e., His, GST, FLAG) and/or fusion partners ...

The protein consists of the Fc region of an IgG1 molecule ... for the development of novel fusion proteins that overcome this challenge. Apogenix’ recombinant TNFSF proteins consist of a single ...

This course introduces students to the principles and practice of recombinant protein expression and purification's. Proteins are major targets of pharmaceuticals, and are themselves increasingly used ...

Key data to be presented at WFH 2025 Comprehensive Care Summit, Dubai, UAE Altuvoct® (efanesoctocog alfa) Location: Great Ballroom .