Researchers from the Babraham Institute, UK, and the German Center for Neurodegenerative Diseases (DZNE) have identified a backup mechanism of protein quality control which prevents the toxic effects ...

A study reveals how proteins form temporary clusters to manage cellular damage, and how disruptions in this process may lead ...

The human body has many important proteins, and insulin and mucin may be among the most crucial. Insulin is generated by beta cells in the pancreas, and regulates the level of glucose in blood, which ...

Understanding a drug’s mechanism of action (MOA) can greatly increase the likelihood of successful clinical trials by identifying biomarkers of patient response and providing a rationale for ...

The immune system is our frontline protection against infection, continually searching for and destroying unknown pathogens.

Future myasthenia gravis therapies have different mechanisms of action than current treatments, said James F. Howard Jr, MD, professor of neurology at the University of North Carolina at Chapel Hill.

A protein plucked from common soil bacteria and paired with a fatty acid can destroy colorectal cancer cells in laboratory ...

New research published in Nature Communications shows how generative AI can be used to design complex dual-action cancer drug candidates. Insilico Medicine has developed a PKMYT1 degrader that both ...

Discover how automated protein analysis is overcoming bottlenecks in drug discovery and translational research, improving ...