A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

After 10 years, members of the 4D Nucleome consortium have successfully completed the first phase of a project that aims to ...

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...